abstract：:Like most intracellular pathogens, the apicomplexan parasites Besnoitia besnoiti, Toxoplasma gondii and Neospora caninum scavenge metabolites from their host cells. Recruitment of the Golgi complex to the vicinity of the parasitophorous vacuole (PV) is likely to aid in this process. In this work, we comparatively asse...

journal_title：Experimental parasitology

authors： Cardoso R,Wang J,Müller J,Rupp S,Leitão A,Hemphill A

更新日期：2018-04-01 00:00:00

abstract：:The water-borne protozoan parasite Cryptosporidium parvum forms oocysts that can persist for long periods of time in the environment, even though the sporozoites inside the oocysts may no longer be viable, making it difficult to assess the associated risk of infection. In this study, we compared the ability of various...

journal_title：Experimental parasitology

authors： Vande Burgt NH,Auer A,Zintl A

更新日期：2018-04-01 00:00:00

abstract：:Amphotericin B (Amp) has been well-successfully used to treat against Leishmania infection, although high toxicity has been found in patients. In the present study, Amp was administered in Leishmania infantum-infected BALB/c mice by three distinct delivery systems aiming to compare their efficacy against challenge inf...

journal_title：Experimental parasitology

authors： Mendonça DVC,Martins VT,Lage DP,Dias DS,Ribeiro PAF,Carvalho AMRS,Dias ALT,Miyazaki CK,Menezes-Souza D,Roatt BM,Tavares CAP,Barichello JM,Duarte MC,Coelho EAF

更新日期：2018-03-01 00:00:00

abstract：:Axenic culture of Leishmania is generally performed in rich, serum-supplemented media which sustain robust growth over multiple passages. The use of such undefined media, however, obscures proteomic analyses and confounds the study of metabolism. We have established a simple, defined culture medium that supports the s...

journal_title：Experimental parasitology

authors： Nayak A,Akpunarlieva S,Barrett M,Burchmore R

更新日期：2018-02-01 00:00:00

abstract：:Acanthamoeba culbertsoni trophozoites, previously isolated from a human keratitis case with severe intraocular damage, were maintained in axenic culture. Co-incubation of amoebae with MDCK cell monolayers demonstrated an apparent preference of the amoebae to introduce themselves between the cells. The trophozoites app...

journal_title：Experimental parasitology

authors： González-Robles A,Omaña-Molina M,Salazar-Villatoro L,Flores-Maldonado C,Lorenzo-Morales J,Reyes-Batlle M,Arnalich-Montiel F,Martínez-Palomo A

更新日期：2017-12-01 00:00:00

abstract：:In order to promote a local Tunisian product, this study was designed to examine, for the first time, the anti-Acanthamoeba activity (Acanthamoeba castellanii Neff) of the essential oils of Tunisian Citrus sinensis peels (Maltese half-blood) and the effect of viroid plant infection on this activity. To do so, three sa...

journal_title：Experimental parasitology

authors： Zouaghi G,Najar A,Chiboub O,Sifaoui I,Abderrabba M,Lorenzo Morales J

更新日期：2017-12-01 00:00:00

abstract：:Free Living Amoebae (FLA) are considered ubiquitous. FLAs may infect various biological organisms which act as reservoir hosts. Infected freshwater fishes can pose a public health concern due to possible human consumption. This study aims to identify possible pathogenic FLAs present in freshwater fishes. Seventy five ...

journal_title：Experimental parasitology

authors： Milanez GD,Masangkay FR,Thomas RC,Ordona MOGO,Bernales GQ,Corpuz VCM,Fortes HSV,Garcia CMS,Nicolas LC,Nissapatorn V

更新日期：2017-12-01 00:00:00

abstract：:Acanthamoeba is a free-living amoeba genus that causes several diseases namely, amoebic keratitis which is a painful sight threatening eyes disease. Its treatment is difficult and the exploration for new drugs is very important. The main objective of the present study was to evaluate the chemical composition of the Es...

journal_title：Experimental parasitology

authors： Souhaiel N,Sifaoui I,Ben Hassine D,Bleton J,Bonose M,Moussa F,Piñero JE,Lorenzo-Morales J,Abderrabba M

更新日期：2017-12-01 00:00:00

abstract：:Acanthamoeba infections cause serious humans diseases, such as amoebic keratitis and granulomatous amoebic encephalitis. Melaleuca essential oil has been reported to be effective in treating bacterial and fungal infections. However, the anti-parasitic effects of this essential oil are not well studied. In the present ...

journal_title：Experimental parasitology

authors： Albouchi F,Sifaoui I,Reyes-Batlle M,López-Arencibia A,Piñero JE,Lorenzo-Morales J,Abderrabba M

更新日期：2017-12-01 00:00:00

abstract：:Transforming growth factor-β (TGF-β) signaling pathway is documented to participate in liver fibrosis via multifactorial mechanisms. microRNA Let-7b (Let-7b) has been proved to alleviate cell fibrosis through regulating TGF-β receptor I (TβRI), but whether it is involved in Schistosomiasis liver fibrosis (SLF) has not...

journal_title：Experimental parasitology

authors： Tang N,Wu Y,Cao W,Liang Y,Gao Y,Hu L,Yang Q,Zhou Y,Tang F,Xiao J

更新日期：2017-11-01 00:00:00

abstract：:Recombinant allergens are currently the best option for serodiagnosis of human anisakiasis in terms of sensitivity and specificity. However, previous reports showed high rates of anisakiasis patients who were negative to Ani s 7 and especially to Ani s 1. Recently, Anisakis haemoglobin was described as a major allerge...

journal_title：Experimental parasitology

authors： González-Fernández J,Rivas L,Luque-Ortega JR,Núñez-Ramírez R,Campioli P,Gárate T,Perteguer MJ,Daschner A,Cuéllar C

更新日期：2017-10-01 00:00:00

abstract：:To better control gastrointestinal nematode infections in humans and animals, it is important to understand the strategies used by these parasites to modulate the host immune system. In this regard, molecules released by parasites have been attributed crucially important roles in host-parasite negotiations. We charact...

journal_title：Experimental parasitology

authors： Tritten L,Tam M,Vargas M,Jardim A,Stevenson MM,Keiser J,Geary TG

更新日期：2017-07-01 00:00:00

abstract：:Standardization of the methods for extraction of DNA from sand flies is essential for obtaining high efficiency during subsequent molecular analyses, such as the new sequencing methods. Information obtained using these methods may contribute substantially to taxonomic, evolutionary, and eco-epidemiological studies. Th...

journal_title：Experimental parasitology

authors： Casaril AE,de Oliveira LP,Alonso DP,de Oliveira EF,Gomes Barrios SP,de Oliveira Moura Infran J,Fernandes WS,Oshiro ET,Ferreira AMT,Ribolla PEM,de Oliveira AG

更新日期：2017-06-01 00:00:00

abstract：:Resistance of human pathogens like Leishmania to drugs is a growing concern where the multidrug-resistant phenotype renders chemotherapy ineffective. The acquired resistance of Leishmania to antimony has promoted intense research on the mechanisms involved but the question has not been resolved yet. In this study we h...

journal_title：Experimental parasitology

authors： Singh N,Sundar S

更新日期：2017-05-01 00:00:00

abstract：:The aim of this study was to evaluate the activity of purinergic enzymes in lymphocytes and cardiac tissue of mice experimentally infected by Trypanosoma cruzi. Twelve female mice were used, divided into two groups (n = 6): uninfected and infected. On day 12 post-infection (PI), the animals were anesthetized and after...

journal_title：Experimental parasitology

authors： do Carmo GM,Doleski PH,de Sá MF,Grando TH,Bottari NB,Leal DB,Gressler LT,Henker LC,Mendes RE,Monteiro SG,Da Silva AS

更新日期：2017-04-01 00:00:00

abstract：:Chemotherapy of food-borne trematodes relies on two drugs, praziquantel and tricabendazole, and there is growing interest in finding alternative therapies. Plant oil extracts have long been used in traditional Chinese medicine as sources of bioactive compounds with antiparasitic activity. Species of the genus Echinost...

journal_title：Experimental parasitology

authors： Souza JG,Lopes Torres EJ,Garcia JS,Gomes AP,Rodrigues-Silva R,Maldonado A Jr,Machado-Silva JR

更新日期：2017-03-01 00:00:00

abstract：:Human cysticercosis caused by Taenia crassiceps is unusual; however, it is an useful experimental model for cysticercosis studies. Benzimidazole derivatives are important antihelminthic drugs widely used against helminths. A novel compound 6-chloro-5-(1-naphthyloxy) -2-(trifluoromethyl)-1H-benzimidazole (RCB20) is a b...

journal_title：Experimental parasitology

authors： Fraga CM,da Costa TL,de Castro AM,Reynoso-Ducoing O,Ambrosio J,Hernández-Campos A,Castillo R,Vinaud MC

更新日期：2017-01-01 00:00:00

abstract：:Chagas' disease is caused by unicellular parasite Trypanosoma cruzi (T. cruzi). It is endemic throughout Latin America, but nowadays has become a global challenge due to tourism and migration. Non-treated infection may result in health-threatening complications and lead to death. Current medications for this infection...

journal_title：Experimental parasitology

authors： Valle-Reyes JS,Melnikov V,Dobrovinskaya O,Rodriguez-Hernández A,Wookee-Zea C,Pimientel-Rodrigez V,Rueda-Valdovinos G,Delgado-Enciso I,López-Lemus UA,Espinoza-Gómez F

更新日期：2017-01-01 00:00:00

abstract：:Benznidazole is the first-line drug used in treating Chagas disease, which is caused by the parasite Trypanosoma cruzi (T. cruzi). However, benznidazole has limited efficacy and several adverse reactions. Pentamidine is an antiprotozoal drug used in the treatment of leishmaniasis and African trypanosomiasis. In T. cru...

journal_title：Experimental parasitology

authors： Seguel V,Castro L,Reigada C,Cortes L,Díaz MV,Miranda MR,Pereira CA,Lapier M,Campos-Estrada C,Morello A,Kemmerling U,Maya JD,López-Muñoz R

更新日期：2016-12-01 00:00:00

abstract：:Tapeworms Taenia solium and Taenia saginata are the causative agents of taeniasis/cysticercosis. These are diseases with high medical and veterinary importance due to their impact on public health and rural economy in tropical countries. The re-emergence of T. solium as a result of human migration, the economic burden...

journal_title：Experimental parasitology

authors： Solano D,Navarro JC,León-Reyes A,Benítez-Ortiz W,Rodríguez-Hidalgo R

更新日期：2016-12-01 00:00:00

abstract：:Nitazoxanide (NTZ) is a broad-spectrum anti-parasitic drug used against a wide variety of protozoans and helminthes. Albendazole, its active metabolite albendazole sulfoxide (ABZSO), is one of the drugs of choice to treat both intestinal and tissue helminth and protozoan infections. However little is known regarding t...

journal_title：Experimental parasitology

authors： Isac E,de A Picanço G,da Costa TL,de Lima NF,de S M M Alves D,Fraga CM,de S Lino Junior R,Vinaud MC

更新日期：2016-12-01 00:00:00

abstract：:Avian coccidiosis is a widespread and economically significant disease of poultry. It is an enteric disease caused by several protozoan Eimeria species. Eimeria belongs to the phylum Apicomplexa, which exhibits an unusual mechanism of host cell invasion. During invasion of host cells, the protein apical membrane antig...

journal_title：Experimental parasitology

authors： Han H,Xue P,Dong H,Zhu S,Zhao Q,Huang B

更新日期：2016-11-01 00:00:00

abstract：:Parasites of wildlife inhabiting urbanised and peri-urban environments are of interest regarding wildlife population health, and also veterinary public health in the case of parasites that can also infect humans and domestic animals. This study aimed to: identify, and estimate the prevalence of, species of Eimeria par...

journal_title：Experimental parasitology

authors： Hillman AE,Yang R,Lymbery AJ,Thompson RCA

更新日期：2016-11-01 00:00:00

abstract：:Most of the drugs used for the treatment of trichinellosis show a limited bioavailability and a high degree of resistance. Therefore, this study aimed to characterize the anthelmintic potential activity of nitazoxanide (NTZ) in a rat model of experimental trichinellosis. Animals were divided into three groups; group I...

journal_title：Experimental parasitology

authors： Ashour DS,Abou Rayia DM,Saad AE,El-Bakary RH

更新日期：2016-11-01 00:00:00

abstract：:Molecular characterizations of Cryptosporidium spp. in ruminants reared under traditional animal management systems are scarce and studies conducted thus far have revealed largely an absence of the pathogenic and zoonotic species Cryptosporidium parvum in pre-weaned animals. In this study, we examined Cryptosporidium ...

journal_title：Experimental parasitology

authors： Taylan-Ozkan A,Yasa-Duru S,Usluca S,Lysen C,Ye J,Roellig DM,Feng Y,Xiao L

更新日期：2016-11-01 00:00:00

abstract：:Because traditional methods used for sewage sludge parasitological examinations have low sensitivity, a new, highly effective method (own method - OM) was devised. The principle of this method is to eliminate the flocculent effect on the structure of sewage sludge by mechanically damaging floccules in the presence of ...

journal_title：Experimental parasitology

authors： Zdybel J,Karamon J,Różycki M,Bilska-Zając E,Kłapeć T,Cencek T

更新日期：2016-11-01 00:00:00

abstract：:Ticks are obligate blood-sucking ectoparasites of a wide range of vertebrates. They can transmit a range of pathogens that cause economic losses to livestock production as well as human disease. In the present study, the complete mitochondrial (mt) genome of Dermacentor silvarum was determined. The mt genome is 14,945...

journal_title：Experimental parasitology

authors： Guo DH,Zhang Y,Fu X,Gao Y,Liu YT,Qiu JH,Chang QC,Wang CR

更新日期：2016-10-01 00:00:00

abstract：:Fasciola hepatica is a digenean trematode which infects a wide variety of domestic animals and also humans. Previous studies have demonstrated that four monoclonal antibodies (Mabs) against the total extract of F. hepatica redia (named as 1E4, 6G11, 4E5 and 4G11) also recognized the excretion - secretion antigens (ES ...

journal_title：Experimental parasitology

authors： Alba A,Sánchez J,Hernández H,Mosqueda M,Rodríguez SY,Capó V,Otero O,Alfonso C,Marcet R,Sarracent J

更新日期：2016-09-01 00:00:00

abstract：:Several species of the genus Leishmania are causative agents of cutaneous leishmaniasis in Pakistan. This study aimed to determine phylogenetic placement of Leishmania species causing cutaneous leishmaniasis in Khyber Pakhtunkhwa province, Pakistan (34 Leishmania tropica, 3 Leishmania infantum), in-relation to species...

journal_title：Experimental parasitology

authors： Khan NH,Messenger LA,Wahid S,Sutherland CJ

更新日期：2016-08-01 00:00:00

abstract：:This study aimed to investigate the effects of diphenyl diselenide (PhSe)2 to treat mice experimentally infected by Toxoplasma gondii on seric biomarkers of cardiac function (creatine kinase, creatine kinase MB, troponin, and myoglobin), and lactate dehydrogenase, as well as to evaluate the enzymatic activity of creat...

journal_title：Experimental parasitology

authors： Machado VS,Bottari NB,Baldissera MD,Isabel de Azevedo M,Rech VC,Ianiski FR,Vaucher RA,Mendes RE,Camillo G,Vogel FF,de la Rue ML,Carmo GM,Tonin AA,Da Silva AS

更新日期：2016-08-01 00:00:00

abstract：:Leishmaniasis are globally widespread parasitic diseases which often leads to death if left untreated. Currently available drugs present different drawbacks, so there is an urgent need to develop new, safe and cost-effective drugs against leishmaniasis. In this study we tested a small library of trans-stilbene and ter...

journal_title：Experimental parasitology

authors： Castelli G,Bruno F,Vitale F,Roberti M,Colomba C,Giacomini E,Guidotti L,Cascio A,Tolomeo M

更新日期：2016-07-01 00:00:00

abstract：:We have characterized a member of the profilin (PROF) family protein as a common antigen in three pathogens-Babesia bovis (B. bovis), Babesia bigemina (B. bigemina), and Babesia microti (B. microti)-and evaluated its immunogenic and cross-protective properties against a challenge infection with B. microti in BALB/c mi...

journal_title：Experimental parasitology

authors： Munkhjargal T,Aboge GO,Ueno A,Aboulaila M,Yokoyama N,Igarashi I

更新日期：2016-07-01 00:00:00

abstract：:In recent years, considerable attention has been given to identify new antileishmanial products derived from medicinal plants, although, to date, no new effective compound has been recently applied to treat leishmaniasis. In the present study, the antileishmanial activity of a water extract from Zingiber officinalis R...

journal_title：Experimental parasitology

authors： Duarte MC,Tavares GS,Valadares DG,Lage DP,Ribeiro TG,Lage LM,Rodrigues MR,Faraco AA,Soto M,da Silva ES,Chávez Fumagalli MA,Tavares CA,Leite JP,Oliveira JS,Castilho RO,Coelho EA

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:It has been reported that behavioral changes relate to infection in different parasitoses. However, the relation between the extent of the behavioral changes and the magnitude of the infection has been scarcely studied. The aim of this study was to evaluate the relationship between different doses of infec...

journal_title：Experimental parasitology

authors： Domínguez-Roldan R,Hallal-Calleros C,Sciutto E,Hernández M,Aguirre-Flores V,García-Jiménez S,Báez-Saldaña A,Flores-Pérez FI

更新日期：2016-07-01 00:00:00

abstract：:Betulinic acid is a pentacyclic triterpenoid with several biological properties already described, including antiparasitic activity. Here, the anti-Trypanosoma cruzi activity of betulinic acid and its semi-synthetic amide derivatives (BA1-BA8) was investigated. The anti-Trypanosoma cruzi activity and selectivity were ...

journal_title：Experimental parasitology

authors： Meira CS,Barbosa-Filho JM,Lanfredi-Rangel A,Guimarães ET,Moreira DR,Soares MB

更新日期：2016-07-01 00:00:00

abstract：:Isospora suis is an intestinal protozoan parasite in pigs. The 2-3 weeks old piglets are most often infected by I. suis because their immune system is not fully developed. The infection exhibits clinical features such as diarrhea and dehydration and seriously affects the economic interests of farmers. The traditional ...

journal_title：Experimental parasitology

authors： Huang C,Wen F,Yue L,Chen R,Zhou W,Hu L,Chen M,Wang S

更新日期：2016-06-01 00:00:00

abstract：:Although few species of Sarcocystis are known to use marsupials of the genus Didelphis as definitive host, an extensive diversity of alleles of surface antigen genes (sag2, sag3, and sag4) has been described in samples of didelphid opossums in Brazil. In this work, we studied 25 samples of Sarcocystis derived from gas...

journal_title：Experimental parasitology

authors： Valadas SY,da Silva JI,Lopes EG,Keid LB,Zwarg T,de Oliveira AS,Sanches TC,Joppert AM,Pena HF,Oliveira TM,Ferreira HL,Soares RM

更新日期：2016-05-01 00:00:00

abstract：:We investigated dried red leaf extracts of Sorghum bicolor for activity against Toxoplasma gondii tachyzoites. S. bicolor red leaf extracts were obtained by bioassay-guided fractionation using ethanol and ethyl acetate as solvents. Analysis of the crude and fractionated extracts from S. bicolor using electrospray ioni...

journal_title：Experimental parasitology

authors： Abugri DA,Witola WH,Jaynes JM,Toufic N

更新日期：2016-05-01 00:00:00

abstract：:The prevalence of Cryptosporidium and microsporidia in feral horses, which have minimal contact with livestock and humans, is not currently known. We report the findings of a study on Cryptosporidium and microsporidia in 34 Mustangs and 50 Chincoteague ponies in the USA. Fecal samples were screened for presence of Cry...

journal_title：Experimental parasitology

authors： Wagnerová P,Sak B,McEvoy J,Rost M,Sherwood D,Holcomb K,Kváč M

更新日期：2016-03-01 00:00:00

abstract：:Rabbit coccidiosis caused by members of the genus Eimeria can cause enormous economic impact worldwide, but the genetics, epidemiology and biology of these parasites remain poorly understood. In the present study, we sequenced and annotated the complete mitochondrial (mt) genomes of five Eimeria species that commonly ...

journal_title：Experimental parasitology

authors： Liu GH,Tian SQ,Cui P,Fang SF,Wang CR,Zhu XQ

更新日期：2015-12-01 00:00:00